Indirect Comparisons and Meta-Analyses

In order to provide proof of evidence-based findings, indirect comparisons and meta-analyses are very important in early benefit assessments, and thus to demonstrate the additional benefit of a new pharmaceutical over the relevant comparative therapy.

The following services are provided by Ecker + Ecker:

• Analysis planning and performance
• Systematic literature search
• Data extraction and validation
• Raw data analysis with SAS and R (e.g. adaptation of population, subgroups, operationalisation of endpoints)
• Indirect comparisons (Bucher´s method, mixed treatment comparison) and meta-analyses
• Assessing indirect comparisons
   

Ecker + Ecker works in accordance with the internationally recognised standards of evidence-based medicine and in line with the G-BA requirements and IQWiG methods paper.

More information about indirect comparisons and meta-analyses (in German)

Please contact

Dr. Christof Ecker
Phone +49 (40) 41 33 081-13